ESR 10: Mate Somlyay - 20 March – 12 May 2017

Title: Synthesis of small fluorinated protein tags

Host University: Durham University, Durham, UK

Accommodation: Ustinov College, Durham University, Durham, UK

Science: Setting up organic reactions under inert atmosphere, monitoring reactions using various MS techniques and NMR. Synthesis and characterization of small CF3- and SF5- substituted thiols from the corresponding bromides for protein tagging. Investigation of Mitsunobu-type reactions on various substrates using nonafluoro-tert-butyl alcohol. Solid-phase peptide synthesis.

New Skills acquired

  • Efficient time management suited for short projects
  • Communicating biological problems to chemists
  • Fast adaptation to new working environment and techniques