Example

Effective methodology for the synthesis of structurally complex, biologically significant substrates bearing fluorine atoms remains a major challenge and essential for life science programmes. In WP4, several complementary strategies for fluorine incorporation will be explored.

Example

Project 4.1 Enzymatic Fluorination - ESR 9, ESR 2
Project 4.2 Synthesis of Aryl-SF5 derivatives - ESR 7
Project 4.3 Synthesis and applications of CF2CF2 transfer agents - ESR 8
Project 4.4 Direct Fluorination using Flow - ESR 4
Project 4.5 Synthesis of novel fluoro-carbohydrates - ESR 5
Project 4.6 Development of biological systems for precursor directed biosynthesis - ESR 3, ESR 4
Project 4.7 Synthesis of fluorinated amino acids - ESR 6
Project 4.8 Synthesis of diverse poly-functionalised fluorinated scaffolds - ESR 1, ESR 8
Project 4.9 Synthesis of fluorinated amine monomers for peptoid design - ESR 2